Pignolo, Robert J: search on Z-Library

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1

Senolytic Drugs: Reducing Senescent Cell Viability to Extend Health Span

Robbins, Paul D., Jurk, Diana, Khosla, Sundeep, Kirkland, James L., LeBrasseur, Nathan K., Miller, Jordan D., Passos, JoÃ£o F., Pignolo, Robert J., Tchkonia, Tamar, Niedernhofer, Laura J.

Journal:

Annual Review of Pharmacology

Year:

2021

File:

PDF, 2.05 MB

2021

2

Fibrodysplasia Ossificans Progressiva: Clinical and Genetic Aspects

Robert J Pignolo, Eileen M Shore, Frederick S Kaplan

Journal:

Orphanet Journal of Rare Diseases

Year:

2011

Language:

english

File:

PDF, 295 KB

english, 2011

3

Imaging assessment of fibrodysplasia ossificans progressiva: Qualitative, quantitative and questionable

Al Mukaddam, Mona, Rajapakse, Chamith S., Pignolo, Robert J., Kaplan, Frederick S., Smith, Stacy E.

Journal:

Year:

2017

Language:

english

File:

PDF, 1.58 MB

english, 2017

4

Clinical-pathological correlations in three patients with fibrodysplasia ossificans progressiva

Wentworth, Kelly L., Bigay, Katherine, Chan, Tea V., Ho, Jennifer P., Morales, Blanca M., Connor, Joseph, Brooks, Erin, Shahriar Salamat, M., Sanchez, Henry Charles, Wool, Geoffrey, Pignolo, Robert J.

Journal:

Year:

2017

Language:

english

File:

PDF, 3.39 MB

english, 2017

5

Exceptional Human Longevity

Pignolo, Robert J.

Journal:

Mayo Clinic Proceedings

Year:

2019

Language:

english

File:

PDF, 491 KB

english, 2019

6

Correction to: Natural history of fibrodysplasia ossificans progressiva: cross-sectional analysis of annotated baseline phenotypes

Pignolo, Robert J., Baujat, Geneviève, Brown, Matthew A., De Cunto, Carmen, Di Rocco, Maja, Hsiao, Edward C., Keen, Richard, Al Mukaddam, Mona, Sang, Kim-Hanh Le Quan, Wilson, Amy, White, Barbara, Gro

Journal:

Orphanet Journal of Rare Diseases

Year:

2019

Language:

english

File:

PDF, 246 KB

english, 2019

7

Correction to: Natural history of fibrodysplasia ossificans progressiva: cross-sectional analysis of annotated baseline phenotypes

Pignolo, Robert J., Baujat, Geneviève, Brown, Matthew A., De Cunto, Carmen, Di Rocco, Maja, Hsiao, Edward C., Keen, Richard, Al Mukaddam, Mona, Sang, Kim-Hanh Le Quan, Wilson, Amy, White, Barbara, Gro

Journal:

Orphanet Journal of Rare Diseases

Year:

2019

File:

PDF, 246 KB

2019

8

Molecular characterization of known and novel ACVR1 variants in phenotypes of aberrant ossification

Gupta, Aditi, Zimmermann, Michael T., Wang, Haitao, Broski, Stephen M., Sigafoos, Ashley N., Macklin, Sarah K., Urrutia, Raul A., Clark, Karl J., Atwal, Paldeep S., Pignolo, Robert J., Klee, Eric W.

Journal:

American Journal of Medical Genetics Part A

Year:

2019

Language:

english

File:

PDF, 4.44 MB

english, 2019

9

Expression of hydrogen peroxide and glutathione metabolizing enzymes in human skin fibroblasts derived from donors of different ages

Bart P. Keogh, R.G. Allen, Robert Pignolo, Joseph Horton, Maria Tresini, Vincent J. Cristofalo

Journal:

Journal of Cellular Physiology

Year:

1996

Language:

english

File:

PDF, 1.24 MB

english, 1996

10

Effects of donor age on the expression of a marker of replicative senescence (EPC-1) in human dermal fibroblasts

Maria Tresini, Robert J. Pignolo, Robert G. Allen, Vincent J. Cristofalo

Journal:

Journal of Cellular Physiology

Year:

1999

Language:

english

File:

PDF, 184 KB

english, 1999

11

Viewing FOP through rosi-colored glasses

Frederick S Kaplan, Robert J Pignolo, Eileen M Shore

Journal:

Journal of Bone and Mineral Research

Year:

2010

Language:

english

File:

PDF, 42 KB

english, 2010

12

Circulating osteogenic cells: Implications for injury, repair, and regeneration

Robert J Pignolo, Moustapha Kassem

Journal:

Journal of Bone and Mineral Research

Year:

2011

Language:

english

File:

PDF, 366 KB

english, 2011

13

Heterozygous inactivation of Gnas in adipose-derived mesenchymal progenitor cells enhances osteoblast differentiation and promotes heterotopic ossification

Robert J Pignolo, Meiqi Xu, Elizabeth Russell, Alec Richardson, Josef Kaplan, Paul C Billings, Frederick S Kaplan, Eileen M Shore

Journal:

Journal of Bone and Mineral Research

Year:

2011

Language:

english

File:

PDF, 473 KB

english, 2011

14

Substance P signaling mediates BMP-dependent heterotopic ossification

Lixin Kan, Vitali Y Lounev, Robert J. Pignolo, Lishu Duan, Yijie Liu, Stuart R. Stock, Tammy L. McGuire, Bao Lu, Norma P. Gerard, Eileen M. Shore, Frederick S. Kaplan, John A. Kessler

Journal:

Journal of Cellular Biochemistry

Year:

2011

Language:

english

File:

PDF, 6.09 MB

english, 2011

15

Putative role for EPC-1/PEDF in the G0 growth arrest of human diploid fibroblasts

Robert J. Pignolo, Mary Kay Francis, Mitch O. Rotenberg, Vincent J. Cristofalo

Journal:

Journal of Cellular Physiology

Year:

2003

Language:

english

File:

PDF, 240 KB

english, 2003

16

Insulin-like growth factor-I: Specific binding to high and low affinity sites and mitogenic action throughout the life span of WI-38 cells

Paul D. Phillips, Robert J. Pignolo, Vincent J. Cristofalo

Journal:

Journal of Cellular Physiology

Year:

1987

Language:

english

File:

PDF, 884 KB

english, 1987

17

Renewed DNA synthesis in senescent WI-38 cells by expression of an inducible chimeric c-fos construct

Paul D. Phillips, Robert J. Pignolo, Kazuko Nishikura, Vincent J. Cristofalo

Journal:

Journal of Cellular Physiology

Year:

1992

Language:

english

File:

PDF, 841 KB

english, 1992

18

Analysis of EPC-1 growth state–dependent expression, specificity, and conservation of related sequences

Robert J. Pignolo, Mitch O. Rotenberg, Vincent J. Cristofalo

Journal:

Journal of Cellular Physiology

Year:

1995

Language:

english

File:

PDF, 921 KB

english, 1995

19

Alterations in the molecular response to DNA damage during cellular aging of cultured fibroblasts: Reduced AP-1 activation and collagenase gene expression

Augustine M. K. Choi, Robert J. Pignolo, Colette M. J. Ap Rhys, Vincent J. Cristofalo, Nikki J. Holbrook

Journal:

Journal of Cellular Physiology

Year:

1995

Language:

english

File:

PDF, 993 KB

english, 1995

20

Expression and regulation of superoxide dismutase activity in human skin fibroblasts from donors of different ages

P. G. Allen, Bart P. Keogh, Glenn S. Gerhard, Robert Pignolo, Joseph Horton, Vincent J. Cristofalo

Journal:

Journal of Cellular Physiology

Year:

1995

Language:

english

File:

PDF, 1.38 MB

english, 1995

21

Circulating Osteogenic Precursor Cells in Heterotopic Bone Formation

Robin K. Suda, Paul C. Billings, Kevin P. Egan, Jung-Hoon Kim, Ruth McCarrick-Walmsley, David L. Glaser, David L. Porter, Eileen M. Shore, Robert J. Pignolo

Journal:

Year:

2009

Language:

english

File:

PDF, 2.10 MB

english, 2009

22

Skeletal metamorphosis in fibrodysplasia ossificans progressiva (FOP)

Frederick S. Kaplan, Qi Shen, Vitali Lounev, Petra Seemann, Jay Groppe, Takenobu Katagiri, Robert J. Pignolo, Eileen M. Shore

Journal:

Journal of Bone and Mineral Metabolism

Year:

2008

Language:

english

File:

PDF, 382 KB

english, 2008

23

Defects in telomere maintenance molecules impair osteoblast differentiation and promote osteoporosis

Robert J. Pignolo, Robin K. Suda, Emily A. McMillan, Johnny Shen, Seoung-Hoon Lee, Yongwon Choi, Alexander C. Wright, F. Brad Johnson

Journal:

Year:

2008

Language:

english

File:

PDF, 1.03 MB

english, 2008

24

Fibrodysplasia ossificans progressiva: a blueprint for metamorphosis

Frederick S. Kaplan, Vitali Y. Lounev, Haitao Wang, Robert J. Pignolo, Eileen M. Shore

Journal:

Annals of the New York Academy of Sciences

Year:

2011

Language:

english

File:

PDF, 174 KB

english, 2011

25

Morphogen Receptor Genes and Metamorphogenes : Skeleton Keys to Metamorphosis

FREDERICK S. KAPLAN, JAY GROPPE, ROBERT J. PIGNOLO, EILEEN M. SHORE

Journal:

Annals of the New York Academy of Sciences

Year:

2007

Language:

english

File:

PDF, 149 KB

english, 2007

26

Animal models of fibrodysplasia ossificans progressiva

Frederick S. Kaplan, Eileen M. Shore, Robert J. Pignolo, David L. Glaser

Journal:

Clinical Reviews in Bone and Mineral Metabolism

Year:

2005

Language:

english

File:

PDF, 51 KB

english, 2005

27

The fibrodysplasia ossificans progressiva lesion

Robert J. Pignolo, Robin K. Suda, Frederick S. Kaplan

Journal:

Clinical Reviews in Bone and Mineral Metabolism

Year:

2005

Language:

english

File:

PDF, 195 KB

english, 2005

28

Introduction

Frederick S. Kaplan, David L. Glaser, Robert J. Pignolo, Eileen M. Shore

Journal:

Clinical Reviews in Bone and Mineral Metabolism

Year:

2005

Language:

english

File:

PDF, 37 KB

english, 2005

29

Immunological features of fibrodysplasia ossificans progressiva and the dysregulated BMP4 pathway

Frederick S. Kaplan, Eileen M. Shore, Rishi Gupta, Paul C. Billings, David L. Glaser, Robert J. Pignolo, Daniel Graf, Malek Kamoun

Journal:

Clinical Reviews in Bone and Mineral Metabolism

Year:

2005

Language:

english

File:

PDF, 56 KB

english, 2005

30

Nonhereditary heterotopic ossificationImplications for Injury, Arthropathy, and Aging

Robert J. Pignolo, Kristin L. Foley

Journal:

Clinical Reviews in Bone and Mineral Metabolism

Year:

2005

Language:

english

File:

PDF, 76 KB

english, 2005

31

Paternally Inherited Gsα Mutation Impairs Adipogenesis and Potentiates a Lean Phenotype In Vivo

Jan-Jan Liu, Elizabeth Russell, Deyu Zhang, Frederick S. Kaplan, Robert J. Pignolo, Eileen M. Shore

Journal:

Year:

2012

Language:

english

File:

PDF, 588 KB

english, 2012

32

Alterations in contact and density-dependent arrest state in senescent WI-38 cells

Robert J. Pignolo, Mitch O. Rotenberg, Vincent J. Cristofalo

Journal:

In Vitro Cellular & Developmental Biology - Animal

Year:

1994

Language:

english

File:

PDF, 604 KB

english, 1994

33

Altered expression of cell cycle dependent genes in senescent WI-38 cells

Paul D. Phillips, Robert J. Pignolo

Journal:

Experimental Gerontology

Year:

1992

Language:

english

File:

PDF, 302 KB

english, 1992

34

Changes in gene expression during senescence in culture

Vincent J. Cristofalo, Robert J. Pignolo, Felicia L. Cianciarulo, Byron R. DiPaolo, Mitch O. Rotenberg

Journal:

Experimental Gerontology

Year:

1992

Language:

english

File:

PDF, 272 KB

english, 1992

35

Molecular markers of senescence in fibroblast-like cultures

Vincent J. Cristofalo, Robert J. Pignolo

Journal:

Experimental Gerontology

Year:

1996

Language:

english

File:

PDF, 1007 KB

english, 1996

36

Fibrodysplasia ossificans progressiva

Frederick S. Kaplan, Martine Le Merrer, David L. Glaser, Robert J. Pignolo, Robert E. Goldsby, Joseph A. Kitterman, Jay Groppe, Eileen M. Shore

Journal:

Best Practice & Research Clinical Rheumatology

Year:

2008

Language:

english

File:

PDF, 270 KB

english, 2008

37

The Pathway of Cell Senescence: WI-38 Cells Arrest in Late G1 and Are Unable to Traverse the Cell Cycle from a True G0 State

Robert J Pignolo, Bernard G Martin, Joseph H Horton, Anne N Kalbach, Vincent J Cristofalo

Journal:

Experimental Gerontology

Year:

1998

Language:

english

File:

PDF, 597 KB

english, 1998

38

Impairment of osteoblast differentiation due to proliferation-independent telomere dysfunction in mouse models of accelerated aging

Haitao Wang, Qijun Chen, Seoung-Hoon Lee, Yongwon Choi, Frederick Brad Johnson, Robert J. Pignolo

Journal:

Year:

2012

Language:

english

File:

PDF, 619 KB

english, 2012

39

Fractures in the Elderly Volume 7390 || Osteobiology of Aging

Pignolo, Robert J., Keenan, Mary Ann, Hebela, Nader M.

Year:

2011

Language:

english

File:

PDF, 1.77 MB

english, 2011

40

Identification of Proteins Differentially Expressed in Quiescent and Proliferatively Senescent Fibroblast Cultures

Byron R. DiPaolo, Robert J. Pignolo, Vincent J. Cristofalo

Journal:

Experimental Cell Research

Year:

1995

File:

PDF, 694 KB

1995

41

Senescent WI-38 Fibroblasts Overexpress LPC-1, a Putative Transmembrane Shock Protein

Robert J. Pignolo, Mitch O. Rotenberg, Joseph H. Horton, Vincent J. Cristofalo

Journal:

Experimental Cell Research

Year:

1998

Language:

english

File:

PDF, 5.51 MB

english, 1998

42

Skin fibroblasts from aged fischer 344 rats undergo similar changes in replicative life span but not immortalization with caloric restriction of donors

Robert J. Pignolo, Edward J. Masoro, Warren W. Nichols, Carole I. Bradt, Vincent J. Cristofalo

Journal:

Experimental Cell Research

Year:

1992

Language:

english

File:

PDF, 2.57 MB

english, 1992

43

Overexpression of the two-chain form of cathepsin B in senescent WI-38 cells

Byron R. Dipaolo, Robert J. Pignolo, Vincent J. Cristofalo

Journal:

Experimental Cell Research

Year:

1992

Language:

english

File:

PDF, 3.37 MB

english, 1992

44

The FOP metamorphogene encodes a novel type I receptor that dysregulates BMP signaling

Frederick S. Kaplan, Robert J. Pignolo, Eileen M. Shore

Journal:

Cytokine & Growth Factor Reviews

Year:

2009

Language:

english

File:

PDF, 356 KB

english, 2009

45

Cloning of the human twist gene: Its expression is retained in adult mesodermally-derived tissues

Sherry M Wang, Vincent W Coljee, Robert J Pignolo, Mitch O Rotenberg, Vincent J Cristofalo, Felipe Sierra

Journal:

Year:

1997

Language:

english

File:

PDF, 588 KB

english, 1997

46

Bone histomorphometry using free and commonly available software

Kevin P Egan, Tracy A Brennan, Robert J Pignolo

Journal:

Year:

2012

Language:

english

File:

PDF, 455 KB

english, 2012

47

Exploring human/animal intersections: Converging lines of evidence in comparative models of aging

John Q. Trojanowski, Joan C. Hendricks, Kathryn Jedrziewski, F. Brad Johnson, Kathryn E. Michel, Rebecka S. Hess, Michael P. Cancro, Meg M. Sleeper, Robert Pignolo, Karen L. Teff, Gustavo D. Aguirre,

Journal:

Alzheimer's & Dementia

Year:

2008

Language:

english

File:

PDF, 80 KB

english, 2008

48

CNS demyelination in fibrodysplasia ossificans progressiva

Kan, Lixin, Kitterman, Joseph A., Procissi, Daniele, Chakkalakal, Salin, Peng, Chian-Yu, McGuire, Tammy L., Goldsby, Robert E., Pignolo, Robert J., Shore, Eileen M., Kaplan, Frederick S., Kessler, Joh

Journal:

Journal of Neurology

Year:

2012

Language:

english

File:

PDF, 1.65 MB

english, 2012

49

Neurological symptoms in individuals with fibrodysplasia ossificans progressiva

Kitterman, Joseph A., Strober, Jonathan B., Kan, Lixin, Rocke, David M., Cali, Amanda, Peeper, Jeannie, Snow, Jennifer, Delai, Patricia L. R., Morhart, Rolf, Pignolo, Robert J., Shore, Eileen M., Kapl

Journal:

Journal of Neurology

Year:

2012

Language:

english

File:

PDF, 278 KB

english, 2012

50

Molecular Changes with in Vitro Cellular Senescence

VINCENT J. CRISTOFALO, ROBERT J. PIGNOLO, MITCH O. ROTENBERG

Journal:

Annals of the New York Academy of Sciences

Year:

1992

Language:

english

File:

PDF, 468 KB

english, 1992